Blood-based CNS regionally and neuronally enriched extracellular vesicles carrying pTau217 for Alzheimer’s disease diagnosis and differential diagnosis

Abstract Accurate differential diagnosis among various dementias is crucial for effective treatment of Alzheimer’s disease (AD). The study began with searching for novel blood-based neuronal extracellular vesicles (EVs) that are more enriched in the brain regions vulnerable to AD development and pro...

Full description

Bibliographic Details
Main Authors: Zhen Guo, Chen Tian, Yang Shi, Xue-Ru Song, Wei Yin, Qing-Qing Tao, Jie Liu, Guo-Ping Peng, Zhi-Ying Wu, Yan-Jiang Wang, Zhen-Xin Zhang, Jing Zhang
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Acta Neuropathologica Communications
Subjects:
Online Access:https://doi.org/10.1186/s40478-024-01727-w