Evaluation of aquaporins in the cerebrospinal fluid in patients with idiopathic normal pressure hydrocephalus.

Brain aquaporin 1 (AQP1) and AQP4 are involved in cerebrospinal fluid (CSF) homeostasis and might participate in the origin of hydrocephalus. Studies have shown alterations of perivascular AQP4 expression in idiopathic normal pressure hydrocephalus (iNPH) and Alzheimer's disease (AD). Due to th...

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Main Authors: Laura Hiraldo-González, José Luis Trillo-Contreras, Pablo García-Miranda, Rocío Pineda-Sánchez, Reposo Ramírez-Lorca, Silvia Rodrigo-Herrero, Magdalena Olivares Blanco, María Oliver, Maria Bernal, Emilio Franco-Macías, Javier Villadiego, Miriam Echevarría
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0258165