Exploring the biological role of postzygotic and germinal de novo mutations in ASD

Exploring the biological role of postzygotic and germinal de novo mutations in ASD

Abstract De novo mutations (DNMs), including germinal and postzygotic mutations (PZMs), are a strong source of causality for Autism Spectrum Disorder (ASD). However, the biological processes involved behind them remain unexplored. Our aim was to detect DNMs (germinal and PZMs) in a Spanish ASD cohor...

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Main Authors: A. Alonso-Gonzalez, M. Calaza, J. Amigo, J. González-Peñas, R. Martínez-Regueiro, M. Fernández-Prieto, M. Parellada, C. Arango, Cristina Rodriguez-Fontenla, A. Carracedo
Format: Article
Language:English
Published: Nature Portfolio 2021-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-79412-w

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https://doi.org/10.1038/s41598-020-79412-w

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