GABRP promotes CD44s-mediated gemcitabine resistance in pancreatic cancer

Background Pancreatic ductal adenocarcinoma (PDAC) has the worst five-year overall survival rate among all cancer types. Acquired chemoresistance is considered one of the main reasons for this dismal prognosis, and the mechanism of chemoresistance is unknown. Methods We previously identified a subpo...

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Bibliographic Details
Main Authors: Chen Chen, Binfeng Wu, Mingge Wang, Jinghua Chen, Zhaohui Huang, Jin-Song Shi
Format: Article
Language:English
Published: PeerJ Inc. 2022-07-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/12728.pdf