Epithelial cell cluster size affects force distribution in response to EGF-induced collective contractility

Epithelial cell cluster size affects force distribution in response to EGF-induced collective contractility

Several factors present in the extracellular environment regulate epithelial cell adhesion and dynamics. Among them, growth factors such as EGF, upon binding to their receptors at the cell surface, get internalized and directly activate the acto-myosin machinery. In this study we present the effects...

Full description

Bibliographic Details
Main Authors: Chiara Zambarda, Carlos Pérez González, Andreas Schoenit, Nisha Veits, Clara Schimmer, Raimund Jung, Dirk Ollech, Joel Christian, Pere Roca-Cusachs, Xavier Trepat, Elisabetta Ada Cavalcanti-Adam
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:European Journal of Cell Biology
Subjects:
Collective contractility
Actomyosin
EGF
Traction forces
Adherens junctions
Micropatterning
Online Access:http://www.sciencedirect.com/science/article/pii/S0171933522000772

Internet

http://www.sciencedirect.com/science/article/pii/S0171933522000772

Similar Items