Epithelial cell cluster size affects force distribution in response to EGF-induced collective contractility

Epithelial cell cluster size affects force distribution in response to EGF-induced collective contractility

Several factors present in the extracellular environment regulate epithelial cell adhesion and dynamics. Among them, growth factors such as EGF, upon binding to their receptors at the cell surface, get internalized and directly activate the acto-myosin machinery. In this study we present the effects...

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Podrobná bibliografie
Hlavní autoři: Chiara Zambarda, Carlos Pérez González, Andreas Schoenit, Nisha Veits, Clara Schimmer, Raimund Jung, Dirk Ollech, Joel Christian, Pere Roca-Cusachs, Xavier Trepat, Elisabetta Ada Cavalcanti-Adam
Médium: Článek
Jazyk:English
Vydáno: Elsevier 2022-09-01
Edice:European Journal of Cell Biology
Témata:
Collective contractility
Actomyosin
EGF
Traction forces
Adherens junctions
Micropatterning
On-line přístup:http://www.sciencedirect.com/science/article/pii/S0171933522000772

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http://www.sciencedirect.com/science/article/pii/S0171933522000772

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