SARS-CoV-2 ORF8 reshapes the ER through forming mixed disulfides with ER oxidoreductases

SARS-CoV-2 ORF8 reshapes the ER through forming mixed disulfides with ER oxidoreductases

The replication machinery of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is closely associated with the endoplasmic reticulum (ER) in host cells. Activation of the unfolded protein response (UPR) is a strategy hijacked by coronavirus to facilitate its replication and suppress ho...

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Bibliographic Details
Main Authors: Ping Liu, Xi Wang, Yiwei Sun, Hongyu Zhao, Fang Cheng, Jifeng Wang, Fuquan Yang, Junjie Hu, Hong Zhang, Chih-chen Wang, Lei Wang
Format: Article
Language:English
Published: Elsevier 2022-08-01
Series:Redox Biology
Subjects:
Endoplasmic reticulum
ORF8
Redox
SARS-CoV-2
Unfolded protein response
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231722001604

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http://www.sciencedirect.com/science/article/pii/S2213231722001604

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