Portable Differential Detection of CTX-M ESBL Gene Variants, blaCTX-M-1 and blaCTX-M-15, from Escherichia coli Isolates and Animal Fecal Samples Using Loop-Primer Endonuclease Cleavage Loop-Mediated Isothermal Amplification

Portable Differential Detection of CTX-M ESBL Gene Variants, blaCTX-M-1 and blaCTX-M-15, from Escherichia coli Isolates and Animal Fecal Samples Using Loop-Primer Endonuclease Cleavage Loop-Mediated Isothermal Amplification

ABSTRACT Cefotaximase-Munich (CTX-M) extended-spectrum beta-lactamase (ESBL) enzymes produced by Enterobacteriaceae confer resistance to clinically relevant third-generation cephalosporins. CTX-M group 1 variants, CTX-M-1 and CTX-M-15, are the leading ESBL-producing Enterobacteriaceae associated wit...

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Bibliographic Details
Main Authors: Owen Higgins, Alexandra Chueiri, Louise O'Connor, Sinéad Lahiff, Liam Burke, Dearbhaile Morris, Nicola Maria Pfeifer, Belén González Santamarina, Christian Berens, Christian Menge, Manuela Caniça, Vera Manageiro, Veljo Kisand, Marwa M. Hassan, Brian Gardner, Arnoud H. M. van Vliet, Roberto M. La Ragione, Bruno Gonzalez-Zorn, Terry J. Smith
Format: Article
Language:English
Published: American Society for Microbiology 2023-02-01
Series:Microbiology Spectrum
Subjects:
AMR
CTX-M
ESBL
Enterobacteriaceae
LAMP
Online Access:https://journals.asm.org/doi/10.1128/spectrum.03316-22

Internet

https://journals.asm.org/doi/10.1128/spectrum.03316-22

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