Bactericidal and anti-biofilm effects of uncharged and cationic ultrasound-responsive nitric oxide microbubbles on Pseudomonas aeruginosa biofilms

Bactericidal and anti-biofilm effects of uncharged and cationic ultrasound-responsive nitric oxide microbubbles on Pseudomonas aeruginosa biofilms

Bacterial biofilms are a major and ongoing concern for public health, featuring both inherited genetic resistance traits and a conferred innate tolerance to traditional antibiotic therapies. Consequently, there is a growing need for novel methods of drug delivery, to increase the efficacy of antimic...

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Bibliographic Details
Main Authors: Gareth LuTheryn, Charlotte Hind, Christopher Campbell, Aaron Crowther, Qiang Wu, Sara B. Keller, Peter Glynne-Jones, J. Mark Sutton, Jeremy S. Webb, Michael Gray, Sandra A. Wilks, Eleanor Stride, Dario Carugo
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
biofilms
nitric oxide (NO)
microbubble (MB)
sonobactericide
chronic wounds
ultrasound
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2022.956808/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2022.956808/full

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