Transcriptional alterations of protein coding and noncoding RNAs in triple negative breast cancer in response to DNA methyltransferases inhibition

Abstract Background DNA methylation plays a crucial role in multiple cellular processes such as gene regulation, chromatin stability, and genetic imprinting. In mammals, DNA methylation is achieved by DNA methyltransferases (DNMTs). A number of studies have associated alterations in DNMT activity to...

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Bibliographic Details
Main Authors: Ramesh Elango, Radhakrishnan Vishnubalaji, Hibah Shaath, Nehad M. Alajez
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Cancer Cell International
Subjects:
Online Access:https://doi.org/10.1186/s12935-021-02213-2