Bufalin Inhibits hTERT Expression and Colorectal Cancer Cell Growth by Targeting CPSF4

Bufalin Inhibits hTERT Expression and Colorectal Cancer Cell Growth by Targeting CPSF4

Background/Aims: Bufalin can induce apoptosis in certain human cancer cell lines, but bufalin has not yet been thoroughly evaluated in colorectal cancer cells. Cleavage and polyadenylation specific factor 4 (CPSF4) and human telomerase reverse transcriptase (hTERT) play important roles in colorectal...

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Bibliographic Details
Main Authors: Ningning Zhang, Yunpeng Xie, Yidi Tai, Yingying Gao, Wei Guo, Wendan Yu, Jia Li, Xu Feng, Jiaojiao Hao, Yue Gao, Xinrui Zhao, Yina Liao, Wei Jiang, Ge Liu, Wuguo Deng, Xiaonan Cui
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2016-12-01
Series:Cellular Physiology and Biochemistry
Subjects:
hTERT
CPSF4
Proliferation
Apoptosis
Migration
Bufalin
Online Access:http://www.karger.com/Article/FullText/453206

Internet

http://www.karger.com/Article/FullText/453206

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