Genetic architecture of human plasma lipidome and its link to cardiovascular disease

Genetic architecture of human plasma lipidome and its link to cardiovascular disease

Cardiovascular diseases (CVD) are associated with plasma lipid levels. Here, Tabassum et al. perform genome-wide association studies for lipidomic profiles with 141 (non-standard) lipid species which highlights shared genetic loci with CVD and that traditional lipids have low genetic correlation wit...

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Bibliographic Details
Main Authors: Rubina Tabassum, Joel T. Rämö, Pietari Ripatti, Jukka T. Koskela, Mitja Kurki, Juha Karjalainen, Priit Palta, Shabbeer Hassan, Javier Nunez-Fontarnau, Tuomo T. J. Kiiskinen, Sanni Söderlund, Niina Matikainen, Mathias J. Gerl, Michal A. Surma, Christian Klose, Nathan O. Stitziel, Hannele Laivuori, Aki S. Havulinna, Susan K. Service, Veikko Salomaa, Matti Pirinen, FinnGen Project, Matti Jauhiainen, Mark J. Daly, Nelson B. Freimer, Aarno Palotie, Marja-Riitta Taskinen, Kai Simons, Samuli Ripatti
Format: Article
Language:English
Published: Nature Portfolio 2019-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-11954-8

Internet

https://doi.org/10.1038/s41467-019-11954-8

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