A protective effect of Gly272Ser polymorphism of GNB3 gene in development of essential hypertension and its relations with environmental hypertension risk factors

A protective effect of Gly272Ser polymorphism of GNB3 gene in development of essential hypertension and its relations with environmental hypertension risk factors

Aim. To study associations of C825T (rs5443) and G272S (rs16932941) polymorphisms of GNB3 gene in Russian population of the Central Chernozem region with essential hypertension (EH) risk; to elicit the role of environmental risk factors in realization of EH predisposition in this gene genotypes carr...

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Main Authors: Aleksey Valer'evich Polonikov, Mariya Andreevna Solodilova, Vladimir Petrovich Ivanov, Aleksandr Mikhaylovich Shestakov, Dmitriy Vladimirovich Ushachev, Ekaterina Konstantinovna Vyalykh, Oksana Vladimirovna Vasil'eva, Natal'ya Vladimirovna Polyakova, Vladimir Vladimirovich Antsupov, Valentina Aleksandrovna Kabanina, Yana Sergeevna Kupriyanova, Irina Viktorovna Bulgakova, Mikhail Alekseevich Kozhukhov, Dmitriy Sergeevich Tevs, A V Polonikov, M A Solodilova, V P Ivanov, A M Shestakov, D V Ushachev, E K Vyalykh, O V Vasilyeva, N V Polyakova, V V Antsupov, V A Kabanina, Ya S Kupriyanova, I V Bulgakova, M A Kozhukhov, D S Tevs
Format: Article
Language:Russian
Published: "Consilium Medicum" Publishing house 2011-04-01
Series:Терапевтический архив
Subjects:
essential hypertension
hereditary predisposition
risk factors
gnb3 gene
genetic polymorphism
association analysis
genotype-environment relations
Online Access:https://ter-arkhiv.ru/0040-3660/article/view/30851

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https://ter-arkhiv.ru/0040-3660/article/view/30851

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