A cross-sectional study to test equivalence of low- versus intermediate-flip angle dynamic susceptibility contrast MRI measures of relative cerebral blood volume in patients with high-grade gliomas at 1.5 Tesla field strength

Introduction1.5 Tesla (1.5T) remain a significant field strength for brain imaging worldwide. Recent computer simulations and clinical studies at 3T MRI have suggested that dynamic susceptibility contrast (DSC) MRI using a 30° flip angle (“low-FA”) with model-based leakage correction and no gadolini...

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Main Authors: Mark S. Shiroishi, Dane Weinert, Steven Y. Cen, Bino Varghese, Timothy Dondlinger, Melissa Prah, Jesse Mendoza, Sina Nazemi, Nima Ameli, Negin Amini, Salman Shohas, Shannon Chen, Bavrina Bigjahan, Gabriel Zada, Thomas Chen, Josh Neman-Ebrahim, Eric L. Chang, Frances E. Chow, Zhaoyang Fan, Wensha Yang, Frank J. Attenello, Jason Ye, Paul E. Kim, Vishal N. Patel, Alexander Lerner, Jay Acharya, Leland S. Hu, C. Chad Quarles, Jerrold L. Boxerman, Ona Wu, Kathleen M. Schmainda
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Oncology
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Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1156843/full