Determination of platinum-resistance of women with ovarian cancer by FTIR spectroscopy combined with multivariate analyses and machine learning methods

Determination of platinum-resistance of women with ovarian cancer by FTIR spectroscopy combined with multivariate analyses and machine learning methods

Abstract Patients with high-grade ovarian cancer have a poor prognosis, thus effective treatment remains an unmet medical issue of high importance. Moreover, finding the reason for resistance to cisplatin is a crucial task for the improvement of anti-cancer drugs. In this study, we showed for the fi...

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Bibliographic Details
Main Authors: Marta Kluz-Barłowska, Tomasz Kluz, Wiesław Paja, Jaromir Sarzyński, Edyta Barnaś, Monika Łączyńska-Madera, Yaroslav Shpotyuk, Ewelina Gumbarewicz, Bartosz Klebowski, Jozef Cebulski, Joanna Depciuch
Format: Article
Language:English
Published: Nature Portfolio 2024-10-01
Series:Scientific Reports
Subjects:
FTIR
Machine learning
PCA
Platinum-resistance women
Ovarian cancer
Online Access:https://doi.org/10.1038/s41598-024-76965-y

Internet

https://doi.org/10.1038/s41598-024-76965-y

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