Study on the liver Drug’s dominant metabolic enzymes for six effective components of the Huang qi Liuyi decoction

Study on the liver Drug’s dominant metabolic enzymes for six effective components of the Huang qi Liuyi decoction

Objective: To investigate the dominant metabolic enzymes of six effective components (astragaloside IV, glycyrrhizic acid, calycosin-glucuronide, formononetin, ononin, calycosin-7-O-β-D- glucoside) of Huangqi Liuyi decoction extract (HQD).Methods: Mouse liver microsomes were prepared. The effects of...

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Bibliographic Details
Main Authors: Qun Wang, Tiantian Tang, Zengguang Wu, Hong Yang, Yuan Gao, Shiyu Zhang, Xinli Song, Xiaolan Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Pharmacology
Subjects:
Huangqi Liuyi decoction
six effective components
CYP450 enzymes
liver microsomal
liver microsomal incubation in vitro
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1175896/full

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https://www.frontiersin.org/articles/10.3389/fphar.2023.1175896/full

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