Microglia ameliorate delirium-like phenotypes in a murine model of acute ventilator-induced lung injury

Abstract Background Delirium affects 50–85% of patients on mechanical ventilation and is associated with increased mortality, prolonged hospitalization, and a three-fold higher risk of dementia. Microglia, the resident immune cells of the brain, exhibit both neuroprotective and neurotoxic functions;...

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Bibliographic Details
Main Authors: Landon Scott, Kevin D. Winzey, Debbie Moreira, Catherine Bresee, Jean‑Philippe Vit, Warren G. Tourtellotte, S. Ananth Karumanchi, Shouri Lahiri
Format: Article
Language:English
Published: BMC 2024-10-01
Series:Journal of Neuroinflammation
Subjects:
Online Access:https://doi.org/10.1186/s12974-024-03260-y