Transcriptome Analysis of Intracellular Amastigotes of Clinical <i>Leishmania infantum</i> Lines from Therapeutic Failure Patients after Infection of Human Macrophages

Transcriptome Analysis of Intracellular Amastigotes of Clinical <i>Leishmania infantum</i> Lines from Therapeutic Failure Patients after Infection of Human Macrophages

Leishmaniasis is considered to be one of the most neglected tropical diseases affecting humans and animals around the world. Due to the absence of an effective vaccine, current treatment is based on chemotherapy. However, the continuous appearance of drug resistance and therapeutic failure (TF) lead...

Full description

Bibliographic Details
Main Authors: Raquel García-Hernández, Ana Perea-Martínez, José Ignacio Manzano, Laura C. Terrón-Camero, Eduardo Andrés-León, Francisco Gamarro
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Microorganisms
Subjects:
<i>Leishmania infantum</i>
intracellular amastigotes
drug-resistant parasites
therapeutic failure clinical parasites
host infection
transcriptomic analysis
Online Access:https://www.mdpi.com/2076-2607/10/7/1304

Internet

https://www.mdpi.com/2076-2607/10/7/1304

Similar Items