Prognostic Value of Association of Copy Number Alterations and Cell-Surface Expression Markers in Newly Diagnosed Multiple Myeloma Patients

Prognostic Value of Association of Copy Number Alterations and Cell-Surface Expression Markers in Newly Diagnosed Multiple Myeloma Patients

Multiple myeloma results from the clonal proliferation of abnormal plasma cells (PCs) in the bone marrow (BM). In this study, the cell surface expression markers (CD) on atypical PCs (detected by multiparametric flow cytometry (MFC)) were correlated with copy number alterations (CNAs) in the genome...

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Bibliographic Details
Main Authors: Mihaiela L. Dragoș, Iuliu C. Ivanov, Mihaela Mențel, Irina C. Văcărean-Trandafir, Adriana Sireteanu, Amalia A. Titianu, Angela S. Dăscălescu, Alexandru B. Stache, Daniela Jitaru, Dragoș L. Gorgan
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:International Journal of Molecular Sciences
Subjects:
multiple myeloma
plasma cells
MLPA
flow cytometry
Online Access:https://www.mdpi.com/1422-0067/23/14/7530

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https://www.mdpi.com/1422-0067/23/14/7530

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