Hepatic stem cells with self-renewal and liver repopulation potential are harbored in CDCP1-positive subpopulations of human fetal liver cells

Hepatic stem cells with self-renewal and liver repopulation potential are harbored in CDCP1-positive subpopulations of human fetal liver cells

Abstract Background Mature human hepatocytes are critical in preclinical research and therapy for liver disease, but are difficult to manipulate and expand in vitro. Hepatic stem cells (HpSCs) may be an alternative source of functional hepatocytes for cell therapy and disease modeling. Since these c...

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Bibliographic Details
Main Authors: Ran-Ran Zhang, Yun-Wen Zheng, Bin Li, Yun-Zhong Nie, Yasuharu Ueno, Tomonori Tsuchida, Hideki Taniguchi
Format: Article
Language:English
Published: BMC 2018-02-01
Series:Stem Cell Research & Therapy
Subjects:
Hepatic stem cells
Transplantation
Drug metabolism
Online Access:http://link.springer.com/article/10.1186/s13287-017-0747-3

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http://link.springer.com/article/10.1186/s13287-017-0747-3

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