Deep Sequencing of Immunoglobulin Genes Identifies a Very Low Percentage of Monoclonal B Cells in Primary Cutaneous Marginal Zone Lymphomas with CD30-Positive Hodgkin/Reed–Sternberg-like Cells

Deep Sequencing of Immunoglobulin Genes Identifies a Very Low Percentage of Monoclonal B Cells in Primary Cutaneous Marginal Zone Lymphomas with CD30-Positive Hodgkin/Reed–Sternberg-like Cells

The spectrum of cutaneous CD30-positive lymphoproliferative disorders encompasses both inflammatory and neoplastic conditions. CD30+ Hodgkin and Reed–Sternberg-like cells have been occasionally reported in primary cutaneous marginal zone lymphoma, where they are thought to represent a side neoplasti...

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Bibliographic Details
Main Authors: Arianna Di Napoli, Evelina Rogges, Niccolò Noccioli, Anna Gazzola, Gianluca Lopez, Severino Persechino, Rita Mancini, Elena Sabattini
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Diagnostics
Subjects:
cutaneous marginal zone lymphoma
Hodgkin and Reed–Stemberg cells
IGH and IGK rearrangements
NGS
Online Access:https://www.mdpi.com/2075-4418/12/2/290

Internet

https://www.mdpi.com/2075-4418/12/2/290

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