Improvement of HEK293 Cell Growth by Adapting Hydrodynamic Stress and Predicting Cell Aggregate Size Distribution

Improvement of HEK293 Cell Growth by Adapting Hydrodynamic Stress and Predicting Cell Aggregate Size Distribution

HEK293 is a widely used cell line in the fields of research and industry. It is assumed that these cells are sensitive to hydrodynamic stress. The aim of this research was to use particle image velocimetry validated computational fluid dynamics (CFD) to determine the hydrodynamic stress in both shak...

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Bibliographic Details
Main Authors: Stefan Seidel, Rüdiger W. Maschke, Fruhar Mozaffari, Regine Eibl-Schindler, Dieter Eibl
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Bioengineering
Subjects:
aggregate size distribution
biochemical engineering
CFD computational fluid dynamics
energy dissipation rate
fluid dynamic stress
HEK293 suspension culture
Online Access:https://www.mdpi.com/2306-5354/10/4/478

Internet

https://www.mdpi.com/2306-5354/10/4/478

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