Fine-Tuning of Piezo1 Expression and Activity Ensures Efficient Myoblast Fusion during Skeletal Myogenesis

Fine-Tuning of Piezo1 Expression and Activity Ensures Efficient Myoblast Fusion during Skeletal Myogenesis

Mechanical stimuli, such as stretch and resistance training, are essential in regulating the growth and functioning of skeletal muscles. However, the molecular mechanisms involved in sensing mechanical stress during muscle formation remain unclear. Here, we investigated the role of the mechanosensit...

Full description

Bibliographic Details
Main Authors: Huascar Pedro Ortuste Quiroga, Massimo Ganassi, Shingo Yokoyama, Kodai Nakamura, Tomohiro Yamashita, Daniel Raimbach, Arisa Hagiwara, Oscar Harrington, Jodie Breach-Teji, Atsushi Asakura, Yoshiro Suzuki, Makoto Tominaga, Peter S. Zammit, Katsumasa Goto
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Cells
Subjects:
skeletal muscle
satellite cells
mechanosensation
Piezo1
Ca<sup>2+</sup> channel
myoblast fusion
Online Access:https://www.mdpi.com/2073-4409/11/3/393

Internet

https://www.mdpi.com/2073-4409/11/3/393

Similar Items