Functional dissection of PRC1 subunits RYBP and YAF2 during neural differentiation of embryonic stem cells

Functional dissection of PRC1 subunits RYBP and YAF2 during neural differentiation of embryonic stem cells

Abstract Polycomb repressive complex 1 (PRC1) comprises two different complexes: CBX-containing canonical PRC1 (cPRC1) and RYBP/YAF2-containing variant PRC1 (vPRC1). RYBP-vPRC1 or YAF2-vPRC1 catalyzes H2AK119ub through a positive-feedback model; however, whether RYBP and YAF2 have different regulato...

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Bibliographic Details
Main Authors: Yanjiang Liu, Gongcheng Hu, Shengxiong Yang, Mingze Yao, Zicong Liu, Chenghong Yan, Yulin Wen, Wangfang Ping, Juehan Wang, Yawei Song, Xiaotao Dong, Guangjin Pan, Hongjie Yao
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-42507-9

Internet

https://doi.org/10.1038/s41467-023-42507-9

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