Entropy-driven cell decision-making predicts ‘fluid-to-solid’ transition in multicellular systems

Entropy-driven cell decision-making predicts ‘fluid-to-solid’ transition in multicellular systems

Cellular decision making allows cells to assume functionally different phenotypes in response to microenvironmental cues, with or without genetic change. It is an open question, how individual cell decisions influence the dynamics at the tissue level. Here, we study spatio-temporal pattern formation...

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Bibliographic Details
Main Authors: Arnab Barua, Simon Syga, Pietro Mascheroni, Nikos Kavallaris, Michael Meyer-Hermann, Andreas Deutsch, Haralampos Hatzikirou
Format: Article
Language:English
Published: IOP Publishing 2020-01-01
Series:New Journal of Physics
Subjects:
cell-decision making
phenotypic plasticity
Langevin equations
mean-field theory
least microEnvironmental uncertainty principle (LEUP)
fluid-to-solid transition
Online Access:https://doi.org/10.1088/1367-2630/abcb2e

Internet

https://doi.org/10.1088/1367-2630/abcb2e

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