Impact of Fluorinated Ionic Liquids on Human Phenylalanine Hydroxylase—A Potential Drug Delivery System

Phenylketonuria (PKU) is an autosomal recessive disease caused by deficient activity of human phenylalanine hydroxylase (hPAH), which can lead to neurologic impairments in untreated patients. Although some therapies are already available for PKU, these are not without drawbacks. Enzyme-replacement t...

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Bibliographic Details
Main Authors: Márcia M. S. Alves, Paula Leandro, Haydyn D. T. Mertens, Ana B. Pereiro, Margarida Archer
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Nanomaterials
Subjects:
Online Access:https://www.mdpi.com/2079-4991/12/6/893