CD8+CD161+ T-Cells: Cytotoxic Memory Cells With High Therapeutic Potential

CD8+CD161+ T-Cells: Cytotoxic Memory Cells With High Therapeutic Potential

NK1.1 and its human homolog CD161 are expressed on NK cells, subsets of CD4+ and CD8+ T cells, and NKT cells. While the expression of NK1.1 is thought to be inhibitory to NK cell function, it is reported to play both costimulatory and coinhibitory roles in T-cells. CD161 has been extensively studied...

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Détails bibliographiques
Auteurs principaux: Vanaja Konduri, Damilola Oyewole-Said, Jonathan Vazquez-Perez, Scott A. Weldon, Matthew M. Halpert, Jonathan M. Levitt, William K. Decker
Format: Article
Langue:English
Publié: Frontiers Media S.A. 2021-02-01
Collection:Frontiers in Immunology
Sujets:
KLRB1
CD161
effector memory
T-cell
TH1 polarization
Accès en ligne:https://www.frontiersin.org/articles/10.3389/fimmu.2020.613204/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2020.613204/full

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