Near-Infrared Optical Imaging of Ovarian Cancer Xenografts with Novel α3-Integrin Binding Peptide “OA02”

Through screening of random one-bead one-compound (OBOC) libraries, we previously identified cyclic peptides with the cDGXGXXc motif that bind to α3 integrin subunit on ovarian adenocarcinoma cell lines ES-2, SKOV-3, and CaOV-3. We subsequently synthesized two secondary libraries based on this motif...

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Bibliographic Details
Main Authors: Olulanu H. Aina, Jan Marik, Regina Gandour-Edwards, Kit S. Lam
Format: Article
Language:English
Published: SAGE Publications 2005-10-01
Series:Molecular Imaging
Online Access:https://doi.org/10.2310/7290.2005.05169