Local application of osteoprotegerin-chitosan gel in critical-sized defects in a rabbit model
Background Osteoprotegerin (OPG) is used for the systemic treatment of bone diseases, although it has many side effects. The aim of this study was to investigate a newly formulated OPG-chitosan gel for local application to repair bone defects. Recent studies have reported that immunodetection of ost...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
PeerJ Inc.
2017-06-01
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Series: | PeerJ |
Subjects: | |
Online Access: | https://peerj.com/articles/3513.pdf |