Local application of osteoprotegerin-chitosan gel in critical-sized defects in a rabbit model

Background Osteoprotegerin (OPG) is used for the systemic treatment of bone diseases, although it has many side effects. The aim of this study was to investigate a newly formulated OPG-chitosan gel for local application to repair bone defects. Recent studies have reported that immunodetection of ost...

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Bibliographic Details
Main Authors: Soher N. Jayash, Najihah M. Hashim, Misni Misran, NA Baharuddin
Format: Article
Language:English
Published: PeerJ Inc. 2017-06-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/3513.pdf