Cortical neurones exhibiting kainate-activated Co2+uptake are selectively vulnerable to AMPA/kainate receptor-mediated toxicity

Cortical neurones exhibiting kainate-activated Co2+uptake are selectively vulnerable to AMPA/kainate receptor-mediated toxicity

Kainate-activated Co2+uptake, a histochemical method that identifies cells bearing Ca2+-permeable AMPA/kainate receptors, labels approximately 15% of murine cortical neurones in cell culture. While exposure times exceeding several hours were needed for AMPA or kainate to destroy most cultured cortic...

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Bibliographic Details
Main Authors: Dorothy M. Turetsky, Lorella M.T. Canzoniero, Stefano L. Sensi, John H. Weiss, Mark P. Goldberg, Dennis W. Choi
Format: Article
Language:English
Published: Elsevier 1994-12-01
Series:Neurobiology of Disease
Subjects:
AMPA
Ca2+
Co2+
glutamate
kainate
neurotoxicity
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996184700131

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http://www.sciencedirect.com/science/article/pii/S0969996184700131

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