Computational analysis of the LRRK2 interactome

LRRK2 was identified in 2004 as the causative protein product of the Parkinson’s disease locus designated PARK8. In the decade since then, genetic studies have revealed at least 6 dominant mutations in LRRK2 linked to Parkinson’s disease, alongside one associated with cancer. It is now well establis...

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Bibliographic Details
Main Authors: Claudia Manzoni, Paul Denny, Ruth C. Lovering, Patrick A. Lewis
Format: Article
Language:English
Published: PeerJ Inc. 2015-02-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/778.pdf