Membrane vesicles derived from Streptococcus suis serotype 2 induce cell pyroptosis in endothelial cells via the NLRP3/Caspase-1/GSDMD pathway

Membrane vesicles derived from Streptococcus suis serotype 2 induce cell pyroptosis in endothelial cells via the NLRP3/Caspase-1/GSDMD pathway

Streptococcus suis serotype 2 (S. suis 2) is a zoonotic pathogen that clinically causes severe swine and human infections (such as meningitis, endocarditis, and septicemia). In order to cause widespread diseases in different organs, S. suis 2 must colonize the host, break the blood barrier, and caus...

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Bibliographic Details
Main Authors: Keda Shi, Yan Li, Minsheng Xu, Kunli Zhang, Hongchao Gou, Chunling Li, Shaolun Zhai
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Journal of Integrative Agriculture
Subjects:
Streptococcus suis serotype 2
membrane vesicles
endocytosis
pyroptosis
NLRP3 inflammasomes
mitochondrial damage
Online Access:http://www.sciencedirect.com/science/article/pii/S2095311923003222

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http://www.sciencedirect.com/science/article/pii/S2095311923003222

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