Biomarkers of central and peripheral inflammation mediate the association between HIV and depressive symptoms

Biomarkers of central and peripheral inflammation mediate the association between HIV and depressive symptoms

Abstract People living with HIV are at increased risk for depression, though the underlying mechanisms for this are unclear. In the general population, depression is associated with peripheral and central inflammation. Given this, and since HIV infection elicits inflammation, we hypothesised that pe...

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Bibliographic Details
Main Authors: Arish Mudra Rakshasa-Loots, Nicholas Bakewell, David J. Sharp, Magnus Gisslén, Henrik Zetterberg, Jasmini Alagaratnam, Ferdinand W. N. M. Wit, Neeltje A. Kootstra, Alan Winston, Peter Reiss, Caroline A. Sabin, Jaime H. Vera, on behalf of the COmorBidity in Relation to AIDS (COBRA) cohort
Format: Article
Language:English
Published: Nature Publishing Group 2023-06-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-023-02489-0

Internet

https://doi.org/10.1038/s41398-023-02489-0

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