Biochemical characterization of type I-E anti-CRISPR proteins, AcrIE2 and AcrIE4

Abstract In bacteria and archaea, CRISPRs and Cas proteins constitute an adaptive immune system against invading foreign genetic materials, such as bacteriophages and plasmids. To counteract CRISPR-mediated immunity, bacteriophages encode anti-CRISPR (Acr) proteins that neutralize the host CRISPR–Ca...

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Bibliographic Details
Main Authors: Jasung Koo, Gyujin Lee, Donghyun Ka, Changkon Park, Jeong-Yong Suh, Euiyoung Bae
Format: Article
Language:English
Published: SpringerOpen 2023-08-01
Series:Applied Biological Chemistry
Subjects:
Online Access:https://doi.org/10.1186/s13765-023-00808-z