Identification of a novel adiponectin receptor and opioid receptor dual acting agonist as a potential treatment for diabetic neuropathy

Identification of a novel adiponectin receptor and opioid receptor dual acting agonist as a potential treatment for diabetic neuropathy

Diabetic neuropathy (DN) is a long-term complication of diabetes mellitus, affecting different periphery nerve systems including sensory and motor neurons. Hyperglycemia is the major cause of DN with symptoms such as weakness of balance or coordination, insensitivity to sensation, weakness of the mu...

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Main Authors: Oscar Ka-Fai Ma, Simone Ronsisvalle, Livia Basile, Ariya Weiman Xiang, Cristina Tomasella, Federica Sipala, Matteo Pappalardo, Koon-Ho Chan, Danilo Milardi, Roy Chun-Laam Ng, Salvatore Guccione
Format: Article
Language:English
Published: Elsevier 2023-02-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Adiponectin
AdipoR agonist
Benzomorphanic derivatives
Opioid receptors
Diabetic Neuropathy
Online Access:http://www.sciencedirect.com/science/article/pii/S075333222201530X

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http://www.sciencedirect.com/science/article/pii/S075333222201530X

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