Toll-like receptor 4 deficiency impairs motor coordination.

Toll-like receptor 4 deficiency impairs motor coordination.

The cerebellum plays an essential role in balance and motor coordination. Purkinje cells (PCs) are the sole output neurons of the cerebellar cortex and are critical for the execution of its functions, including motor coordination. Toll-like receptor 4 (TLR) 4 is involved in the innate immune respons...

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Bibliographic Details
Main Authors: Jianwei eZhu, Yifei eLi, Zhaotao eWang, Weiqiang eJia, Ruxiang eXu
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-02-01
Series:Frontiers in Neuroscience
Subjects:
Cerebellum
Purkinje Cells
TLR4
motor coordination
Bergmann glia
granule cell
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnins.2016.00033/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnins.2016.00033/full

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