Gene–gene interaction of AhRwith and within the Wntcascade affects susceptibility to lung cancer

Gene–gene interaction of AhRwith and within the Wntcascade affects susceptibility to lung cancer

Abstract Background Aberrant Wnt signalling, regulating cell development and stemness, influences the development of many cancer types. The Aryl hydrocarbon receptor (AhR) mediates tumorigenesis of environmental pollutants. Complex interaction patterns of genes assigned to AhR/Wnt-signalling were re...

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Bibliographic Details
Main Authors: Albert Rosenberger, Nils Muttray, Rayjean J. Hung, David C. Christiani, Neil E. Caporaso, Geoffrey Liu, Stig E. Bojesen, Loic Le Marchand, Demetrios Albanes, Melinda C. Aldrich, Adonina Tardon, Guillermo Fernández-Tardón, Gad Rennert, John K. Field, Michael P. A. Davies, Triantafillos Liloglou, Lambertus A. Kiemeney, Philip Lazarus, Bernadette Wendel, Aage Haugen, Shanbeh Zienolddiny, Stephen Lam, Matthew B. Schabath, Angeline S. Andrew, Eric J. Duell, Susanne M. Arnold, Gary E. Goodman, Chu Chen, Jennifer A. Doherty, Fiona Taylor, Angela Cox, Penella J. Woll, Angela Risch, Thomas R. Muley, Mikael Johansson, Paul Brennan, Maria Teresa Landi, Sanjay S. Shete, Christopher I. Amos, Heike Bickeböller, The INTEGRAL-ILCCO Consortium
Format: Article
Language:English
Published: BMC 2022-01-01
Series:European Journal of Medical Research
Subjects:
Susceptibility
Association
Gene–gene integration
Prediction
Polygenic risk score
Decision trees
Online Access:https://doi.org/10.1186/s40001-022-00638-7

Internet

https://doi.org/10.1186/s40001-022-00638-7

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