A novel cell lysis approach reveals that caspase-2 rapidly translocates from the nucleus to the cytoplasm in response to apoptotic stimuli.
Unlike other caspases, caspase-2 appears to be a nuclear protein although immunocytochemical studies have suggested that it may also be localized to the cytosol and golgi. Where and how caspase-2 is activated in response to apoptotic signals is not clear. Earlier immunocytochemistry studies suggest...
Prif Awduron: | , |
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Fformat: | Erthygl |
Iaith: | English |
Cyhoeddwyd: |
Public Library of Science (PLoS)
2013-01-01
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Cyfres: | PLoS ONE |
Mynediad Ar-lein: | http://europepmc.org/articles/PMC3626589?pdf=render |