Synthesis of New 1,2,3,4-Tetrahydroquinoline Hybrid of Ibuprofen and Its Biological Evaluation

Synthesis of New 1,2,3,4-Tetrahydroquinoline Hybrid of Ibuprofen and Its Biological Evaluation

Herein we report the obtaining of 1-(3,4-dihydroquinolin-1(2H)-yl)-2- (4-isobutylphenyl)propan-1-one and its characterization. The newly obtained hybrid and its derivatives (hybrids of ibuprofen with 1,2,3,4-tetrahydroisoquinoline, and piperidine) were screened for their in vitro antioxidant, antitr...

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Bibliographic Details
Main Authors: Stanimir Manolov, Iliyan Ivanov, Dimitar Bojilov
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Molbank
Subjects:
quinoline
ibuprofen
hybrid molecule
in silico
in vitro
antioxidant
Online Access:https://www.mdpi.com/1422-8599/2022/1/M1350

Internet

https://www.mdpi.com/1422-8599/2022/1/M1350

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