PBK/TOPK Inhibitor Suppresses the Progression of Prolactinomas

BackgroundProlactinoma is the most common type of pituitary tumors, and its resultant tumor occupying and hormone disturbance greatly damage the health of patients. In this study, we investigated a protein kinase-PDZ Binding Kinase (PBK)/T-LAK Cell-Originated Protein Kinase (TOPK) as a candidate pro...

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Bibliographic Details
Main Authors: Kejing Zhu, Xueting Cheng, Shuman Wang, Hong Zhang, Yu Zhang, Xiong Wang, Yonggang Chen, Jinhu Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2021.706909/full