Chemical modifications of a natural xanthone and antimicrobial activity against multidrug resistant Staphylococcus aureus and cytotoxicity against human tumor cell lines

A series of 15 ω-aminoalkoxylxanthones containing methyl, ethyl, propyl, tert-butylamino and piperidinyl moieties were synthesized from a natural xanthone isolated from a lichen species. These compounds were tested for their in vitro antibacterial properties against Gram-positive and Gram-negative b...

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Main Authors: Ana Camila Micheletti, Neli Kika Honda, Dênis Pires de Lima, Adilson Beatriz, Maria Rita Sant'ana, Nadia Cristina Pereira Carvalho, Maria de Fatima Cepa Matos, Lyara Meira Marinho Queiróz, Danielle Bogo, José Roberto Zorzatto
Format: Article
Language:English
Published: Sociedade Brasileira de Química 2011-01-01
Series:Química Nova
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422011000600019&lng=en&tlng=en