MitoQ inhibits hepatic stellate cell activation and liver fibrosis by enhancing PINK1/parkin-mediated mitophagy

Mitophagy affects the activation of hepatic stellate cells (HSCs). Mitochondria-targeted ubiquinone (MitoQ) is a mitochondria-targeted antioxidant that reduces the production of intracellular reactive oxygen species (ROS). However, its relationship with mitophagy remains unclear. This study evaluate...

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Bibliographic Details
Main Authors: Dou Shi-Ying, Zhang Jiu-Na, Xie Xiao-Li, Liu Ting, Hu Jun-Li, Jiang Xiao-Yu, Wang Miao-Miao, Jiang Hui-Qing
Format: Article
Language:English
Published: De Gruyter 2021-11-01
Series:Open Medicine
Subjects:
Online Access:https://doi.org/10.1515/med-2021-0394