IL-39 promotes chronic graft-versus-host disease by increasing T and B Cell pathogenicity

IL-39 promotes chronic graft-versus-host disease by increasing T and B Cell pathogenicity

Abstract Background Chronic graft-versus-host disease (cGVHD) remains a major complication during the late phase of allogeneic hematopoietic stem cell transplantation (allo-HSCT). IL-39, a newly described pro-inflammatory cytokine belonging to the IL-12 family, plays a role in lupus development. Rec...

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Bibliographic Details
Main Authors: Kangkang Lv, Bo Hu, Mingzhu Xu, Li Wan, Ziqi Jin, Mimi Xu, Yuanyuan Du, Kunpeng Ma, Quansheng Lv, Yang Xu, Lei Lei, Huanle Gong, Haiyan Liu, Depei Wu, Yuejun Liu
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Experimental Hematology & Oncology
Subjects:
IL-39
IL-12
Chronic graft-versus-host disease
Allogeneic hematopoietic stem cell transplantation
Online Access:https://doi.org/10.1186/s40164-022-00286-x

Internet

https://doi.org/10.1186/s40164-022-00286-x

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