Differential Biodistribution of Adenoviral-Vectored Vaccine Following Intranasal and Endotracheal Deliveries Leads to Different Immune Outcomes

Differential Biodistribution of Adenoviral-Vectored Vaccine Following Intranasal and Endotracheal Deliveries Leads to Different Immune Outcomes

Infectious diseases of the respiratory tract are one of the top causes of global morbidity and mortality with lower respiratory tract infections being the fourth leading cause of death. The respiratory mucosal (RM) route of vaccine delivery represents a promising strategy against respiratory infecti...

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Détails bibliographiques
Auteurs principaux: Vidthiya Jeyanathan, Sam Afkhami, Michael R. D’Agostino, Anna Zganiacz, Xueya Feng, Matthew S. Miller, Mangalakumari Jeyanathan, Michael R. Thompson, Zhou Xing
Format: Article
Langue:English
Publié: Frontiers Media S.A. 2022-06-01
Collection:Frontiers in Immunology
Sujets:
respiratory mucosal immunization
intranasal
endotracheal
biodistribution
Adenovirus-vectored vaccine
Tuberculosis
Accès en ligne:https://www.frontiersin.org/articles/10.3389/fimmu.2022.860399/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.860399/full

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