Hepatitis C virus NS3/4A inhibitors and other drug-like compounds as covalent binders of SARS-CoV-2 main protease

Abstract Severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2), which causes coronavirus disease 2019 (COVID-19), threatens global public health. The world needs rapid development of new antivirals and vaccines to control the current pandemic and to control the spread of the variants. Among t...

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Bibliographic Details
Main Authors: Babak Andi, Desigan Kumaran, Dale F. Kreitler, Alexei S. Soares, Jantana Keereetaweep, Jean Jakoncic, Edwin O. Lazo, Wuxian Shi, Martin R. Fuchs, Robert M. Sweet, John Shanklin, Paul D. Adams, Jurgen G. Schmidt, Martha S. Head, Sean McSweeney
Format: Article
Language:English
Published: Nature Portfolio 2022-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-15930-z