Glycan modification of glioblastoma-derived extracellular vesicles enhances receptor-mediated targeting of dendritic cells

Glycan modification of glioblastoma-derived extracellular vesicles enhances receptor-mediated targeting of dendritic cells

Glioblastoma is the most prevalent and aggressive primary brain tumour for which total tumour lysate-pulsed dendritic cell vaccination is currently under clinical evaluation. Glioblastoma extracellular vesicles (EVs) may represent an enriched cell-free source of tumour-associated (neo-) antigens to...

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Bibliographic Details
Main Authors: Sophie A. Dusoswa, Sophie K. Horrevorts, Martino Ambrosini, Hakan Kalay, Nanne J. Paauw, Rienk Nieuwland, Michiel D. Pegtel, Tom Würdinger, Yvette Van Kooyk, Juan J. Garcia-Vallejo
Format: Article
Language:English
Published: Wiley 2019-12-01
Series:Journal of Extracellular Vesicles
Subjects:
glioblastoma
glioma
extracellular vesicles
ev
glycans
dendritic cells
dc
cancer vaccine
Online Access:http://dx.doi.org/10.1080/20013078.2019.1648995

Internet

http://dx.doi.org/10.1080/20013078.2019.1648995

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