Structural Modifications on Chalcone Framework for Developing New Class of Cholinesterase Inhibitors

Structural Modifications on Chalcone Framework for Developing New Class of Cholinesterase Inhibitors

Due to the multifaceted pharmacological activities of chalcones, these scaffolds have been considered one of the most privileged frameworks in the drug discovery process. Structurally, chalcones are α, β-unsaturated carbonyl functionalities with two aryl or heteroaryl units. Amongst the numerous pha...

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Bibliographic Details
Main Authors: Ginson George, Vishal Payyalot Koyiparambath, Sunitha Sukumaran, Aathira Sujathan Nair, Leena K. Pappachan, Abdullah G. Al-Sehemi, Hoon Kim, Bijo Mathew
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:International Journal of Molecular Sciences
Subjects:
chalcones
acetylcholinesterase
butyrylcholinesterase
structure activity relationships
Online Access:https://www.mdpi.com/1422-0067/23/6/3121

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https://www.mdpi.com/1422-0067/23/6/3121

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