A Leishmania-specific hypothetical protein expressed in both promastigote and amastigote stages of Leishmania infantum employed for the serodiagnosis of, and as a vaccine candidate against, visceral leishmaniasis

A Leishmania-specific hypothetical protein expressed in both promastigote and amastigote stages of Leishmania infantum employed for the serodiagnosis of, and as a vaccine candidate against, visceral leishmaniasis

Abstract Background LiHyV is an antigenic hypothetical protein present in both promastigote and amastigote stages of Leishmania infantum, which was recently identified by an immunoproteomic approach. A recombinant version of this protein (rLiHyV) was evaluated as a diagnostic marker for canine VL (C...

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Main Authors: Vivian T. Martins, Mariana C. Duarte, Miguel A. Chávez-Fumagalli, Daniel Menezes-Souza, Cecília S. P. Coelho, Danielle F. de Magalhães-Soares, Ana Paula Fernandes, Manuel Soto, Carlos A. P. Tavares, Eduardo A. F. Coelho
Format: Article
Language:English
Published: BMC 2015-07-01
Series:Parasites & Vectors
Subjects:
Leishmania spp
Hypothetical proteins
BALB/c mice
Vaccine
Serodiagnosis
Canine visceral leishmaniasis
Online Access:https://doi.org/10.1186/s13071-015-0964-5

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https://doi.org/10.1186/s13071-015-0964-5

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