Regulatory factor identification for nodal genes in zebrafish by causal inference

Activation of nodal genes is critical for mesoderm and endoderm induction. Our previous study reported that zebrafish nodal genes ndr1/squint and ndr2/cyclops are coordinately regulated by maternal Eomesa, Hwa-activated β-catenin (Hwa/β-catenin) signaling, and Nodal autoregulation (Nodal/Smad2) sign...

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Bibliographic Details
Main Authors: Cencan Xing, Zehua Zeng, Yaqi Li, Bo Gong, Weimin Shen, Roshan Shah, Lu Yan, Hongwu Du, Anming Meng
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.1047363/full