Folic Acid Treatment Directly Influences the Genetic and Epigenetic Regulation along with the Associated Cellular Maintenance Processes of HT-29 and SW480 Colorectal Cancer Cell Lines

Folic Acid Treatment Directly Influences the Genetic and Epigenetic Regulation along with the Associated Cellular Maintenance Processes of HT-29 and SW480 Colorectal Cancer Cell Lines

Folic acid (FA) is a synthetic form of vitamin B9, generally used as a nutritional supplement and an adjunctive medication in cancer therapy. FA is involved in genetic and epigenetic regulation; therefore, it has a dual modulatory role in established neoplasms. We aimed to investigate the effect of...

Full description

Bibliographic Details
Main Authors: Sára Zsigrai, Alexandra Kalmár, Barbara K. Barták, Zsófia B. Nagy, Krisztina A. Szigeti, Gábor Valcz, William Kothalawala, Titanilla Dankó, Anna Sebestyén, Gábor Barna, Orsolya Pipek, István Csabai, Zsolt Tulassay, Péter Igaz, István Takács, Béla Molnár
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Cancers
Subjects:
colorectal cancer
folic acid
genomic stability
DNA methylation
gene expression
Online Access:https://www.mdpi.com/2072-6694/14/7/1820

Internet

https://www.mdpi.com/2072-6694/14/7/1820

Similar Items